Detalhe da pesquisa
1.
Safety, tolerability, and pharmacokinetics of Aurora kinase B inhibitor AZD2811: a phase 1 dose-finding study in patients with advanced solid tumours.
Br J Cancer
; 128(10): 1906-1915, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36871042
2.
A Phase Ib Dose-Escalation Study of LCL161 Plus Oral Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies.
Oncologist
; 28(7): 640-e559, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37129455
3.
A phase Ib study of adavosertib, a selective Wee1 inhibitor, in patients with locally advanced or metastatic solid tumors.
Invest New Drugs
; 41(3): 493-502, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37171722
4.
Discordance in Tumor Mutation Burden from Blood and Tissue Affects Association with Response to Immune Checkpoint Inhibition in Real-World Settings.
Oncologist
; 27(3): 175-182, 2022 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35274716
5.
A real-world retrospective study of the use of Ki-67 testing and treatment patterns in patients with HR+, HER2- early breast cancer in the United States.
BMC Cancer
; 22(1): 502, 2022 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35524219
6.
Phase Ib study of the MEK inhibitor cobimetinib (GDC-0973) in combination with the PI3K inhibitor pictilisib (GDC-0941) in patients with advanced solid tumors.
Invest New Drugs
; 38(2): 419-432, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31020608
7.
A Randomized, Double-Blinded, Phase II Trial of Carboplatin and Pemetrexed with or without Apatorsen (OGX-427) in Patients with Previously Untreated Stage IV Non-Squamous-Non-Small-Cell Lung Cancer: The SPRUCE Trial.
Oncologist
; 24(12): e1409-e1416, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31420467
8.
Comparing the relation between ultrasound-estimated fetal weight and birthweight in cohort of small-for-gestational-age fetuses.
Acta Obstet Gynecol Scand
; 98(11): 1435-1441, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31090917
9.
Detection of Two Peronospora spp., Responsible for Downy Mildew, in Opium Poppy Seed.
Plant Dis
; 102(11): 2277-2284, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30211657
10.
A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor.
Br J Cancer
; 116(5): 575-583, 2017 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28152546
11.
Phase 1, open-label, dose escalation, safety, and pharmacokinetics study of ME-344 as a single agent in patients with refractory solid tumors.
Cancer
; 121(7): 1056-63, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25411085
12.
A phase I dose-escalation study to assess safety, tolerability, pharmacokinetics, and preliminary efficacy of the dual mTORC1/mTORC2 kinase inhibitor CC-223 in patients with advanced solid tumors or multiple myeloma.
Cancer
; 121(19): 3481-90, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26177599
13.
A phase Ib study of linsitinib (OSI-906), a dual inhibitor of IGF-1R and IR tyrosine kinase, in combination with everolimus as treatment for patients with refractory metastatic colorectal cancer.
Invest New Drugs
; 33(1): 187-93, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25335932
14.
A phase 1 study of the sachet formulation of the oral dual PI3K/mTOR inhibitor BEZ235 given twice daily (BID) in patients with advanced solid tumors.
Invest New Drugs
; 33(2): 463-71, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25707361
15.
A first-in-human phase I dose-escalation, pharmacokinetic, and pharmacodynamic evaluation of intravenous LY2090314, a glycogen synthase kinase 3 inhibitor, administered in combination with pemetrexed and carboplatin.
Invest New Drugs
; 33(6): 1187-96, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26403509
16.
A phase I study of VS-6063, a second-generation focal adhesion kinase inhibitor, in patients with advanced solid tumors.
Invest New Drugs
; 33(5): 1100-7, 2015 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26334219
17.
A Phase I Study of the Hsp90 Inhibitor AUY922 plus Capecitabine for the Treatment of Patients with Advanced Solid Tumors.
Cancer Invest
; 33(10): 477-82, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26460795
18.
Characterization of mating type genes supports the hypothesis that Stagonosporopsis chrysanthemi is homothallic and provides evidence that Stagonosporopsis tanaceti is heterothallic.
Curr Genet
; 60(4): 295-302, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24974310
19.
A first-in-human dose-escalation study of ME-143, a second generation NADH oxidase inhibitor, in patients with advanced solid tumors.
Invest New Drugs
; 32(1): 87-93, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23525756
20.
Everolimus in Breast Cancer: The Role of the Pharmacist.
Ann Pharmacother
; 48(9): 1194-1201, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25007922